TRAMADOL: WHAT YOU NEED TO KNOW

Tramadol is an opioid-like pain drug used to treat moderately severe pain. It modifies the processing of pain signals between the nerves and the brain. However, it has several different targets in the nervous system—each imparting contributions to tramadol’s pain relieving and, sometimes, mood altering properties.

Two well-known effects of tramadol are considered to be the most relevant for its ability to relieve pain and encourage abuse. First, like heroin, codeine, and all other opiate analgesics, it binds to the opioid receptor. Second, it inhibits the reuptake of serotonin and norepinephrine. This gives both the pain-relieving effects that patients need and, at higher doses, the euphoric (with the increase levels of serotonin and norepinephrine in the brain) effects that abusers seek. For some individuals, these pleasant symptoms serve to reinforce a pattern of continued tramadol use.

Side Effects of Tramadol

Some potential side effects of tramadol include: Dizziness, Difficulty falling asleep, Headache, Constipation, Diarrhoea, Loss of appetite, Sweating, Dry mouth, Tremulousness, Nausea etc

Long-Term Effects of Tramadol

These effects may vary, but they often include:

• Tolerance: As the body adapts to tramadol's presence, users need larger doses of the drug to feel its painkilling and euphoric effects.
• Physical dependence: Along with tolerance, many users experience physical dependence if they use tramadol for a long period of time. Their bodies adapt to the presence of the drug, and soon require tramadol in order to function properly. If a dependent individual stops taking tramadol, they may become physically ill due to the onset of a withdrawal syndrome.
• Cognitive decline: Many opioid drugs are associated with cognitive impairment and slowed reaction times. Complex tasks may become more difficult with long-term use of tramadol, and users may present a danger to themselves or others when driving.

The side effects of tolerance and dependence may ultimately lead to a tramadol addiction.

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